Extracorporeal Membrane Oxygenation (ECMO) devices and heart-lung machines are critical tools in cardiopulmonary bypass management, temporarily taking over the functions of the heart and/or lungs. Both systems divert venous blood from the patient, process it externally, and return it as oxygenated blood, allowing the native organs to rest and heal during severe conditions or open-heart surgeries. A typical circuit involves cannulas (tubes) inserted into large blood vessels to draw deoxygenated blood and return oxygenated blood. This blood flows through a pump (either roller or centrifugal) that mimics the heart's pumping action. Next, it passes through an oxygenator (artificial lung), a crucial component where carbon dioxide is removed and oxygen is added via a semi-permeable membrane. Many systems also incorporate a heat exchanger to regulate blood temperature, which is vital for organ protection. While both serve to support cardiopulmonary function, heart-lung machines are generally used for shorter durations, primarily during complex cardiac surgeries where the heart needs to be still. ECMO, however, provides prolonged support (days to weeks) for life-threatening heart and lung conditions, acting as a bridge to recovery, transplant, or further decision-making. Developing advanced ECMO devices focuses on enhancing biocompatibility, minimizing complications like bleeding and clotting, and improving patient outcomes.
Show MoreYear of Establishment2023